PURPOSE what is the prognosis of mild cognitive impairment?
METHODS 357 patients with MCI aged 75 years or older with follow-up for 3 years.
RESULTS Overall, 41.5% of the patients had remission of symptoms with normal cognitive function 1.5 and 3 years later, 21.3% showed a fluctuating course, 14.8% had stable symptoms, and 22.4% had progression to dementia. Patients were at higher risk for advancing if they had symptoms of depression, impairment in more than 1 cognitive domain, or more severe cognitive impairment, or were older.
CONCLUSIONS In primary care, about one-quarter of patients with MCI progress to dementia within 3 years. Do not forget: three-quarters of patients with MCI stayed cognitively stable or even improved within 3 years.
Ann Fam Med. 2014 Mar-Apr;12(2):158-65