Tuesday, November 11, 2014

Muscle-strengthening and conditioning activities and risk of type 2 diabetes: a prospective study in two cohorts of US women.

BACKGROUND: aerobic physical activity lowers the risk of type 2 diabetes. Do muscle-strengthening activities lower the risk as well?

METHODS: 99,316 women were followed-up for 8 years from the Nurses' Health Study ([NHS] aged 53-81 years, 2000-2008) and Nurses' Health Study II ([NHSII] aged 36-55 years, 2001-2009). The women were free of diabetes, cancer, and cardiovascular diseases at baseline.

RESULTS: the pooled relative risk (RR) for T2D for women performing 1-29, 30-59, 60-150, and >150 min/week of total muscle-strengthening and conditioning activities was 0.83, 0.93, 0.75, and 0.60 compared to women reporting no muscle-strengthening and conditioning activities (p<0.001 for trend). Women who engaged in at least 150 min/week of aerobic MVPA and at least 60 min/week of muscle-strengthening activities had substantial risk reduction compared with inactive women (pooled RR = 0.33).

CONCLUSIONS: muscle-strengthening and conditioning activities are associated with a lower risk of developing type 2 diabetes mellitus.

PLoS Med. 2014 Jan;11(1):e1001587