Friday, October 28, 2016

CT Angiography in Acute Chest Pain.

CT angiography of the heart reduced the need for coronary angiography from 100% to 14%. After a median follow-up of 3.3 years, there was no significant difference in major adverse cardiac events between those undergoing CT angiography versus those undergoing conventional coronary angiography (4.2% vs 3.7%, p=0.86). BMJ. 2016 Oct 24;355:i5441

Comment: This is a good use of technology: using a non-invasive study (CT Angiography) to decrease the need for a more invasive approach. The health benefit was a shorter hospitalization, a non-invasive approach, with no increase (or decrease) in adverse health events over a 3-year follow-up period.

Tuesday, October 25, 2016

B Complex Vitamins and the Brain

Vitamin B complex deficiency is common. In the absence of an optimal diet, this author suggests that it is reasonable to take a B complex dietary supplement at doses greatly in excess of current governmental recommendations to preserve brain health. Nutrients. 2016 Jan 27;8(2):68

Comment: Most people believe that taking a B complex supplement is safe, given that they are water soluble. However, to my knowledge there are no long-term studies looking at the benefits or risks. While this author suggests a significant benefit greater than risks, it seems prudent that if you take a B complex supplement, that you should take regular breaks or holidays from the supplement regimen to allow the washout of any buildup, and continue to receive regular medical care including blood testing.